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Zebrafish modeling of intestinal injury, bacterial exposures and medications defines epithelial in vivo responses relevant to human inflammatory bowel disease

Genome-wide association studies have identified over 200 genomic loci associated with inflammatory bowel disease (IBD). High-effect risk alleles define key roles for genes involved in bacterial response and innate defense. More high-throughput in vivo systems are required to rapidly evaluate therape...

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Detalles Bibliográficos
Autores principales: Chuang, Ling-shiang, Morrison, Joshua, Hsu, Nai-yun, Labrias, Philippe Ronel, Nayar, Shikha, Chen, Ernie, Villaverde, Nicole, Facey, Jody Ann, Boschetti, Gilles, Giri, Mamta, Castillo-Martin, Mireia, Thin, Tin Htwe, Sharma, Yashoda, Chu, Jaime, Cho, Judy H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6737949/
https://www.ncbi.nlm.nih.gov/pubmed/31337664
http://dx.doi.org/10.1242/dmm.037432