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Zebrafish modeling of intestinal injury, bacterial exposures and medications defines epithelial in vivo responses relevant to human inflammatory bowel disease
Genome-wide association studies have identified over 200 genomic loci associated with inflammatory bowel disease (IBD). High-effect risk alleles define key roles for genes involved in bacterial response and innate defense. More high-throughput in vivo systems are required to rapidly evaluate therape...
Autores principales: | Chuang, Ling-shiang, Morrison, Joshua, Hsu, Nai-yun, Labrias, Philippe Ronel, Nayar, Shikha, Chen, Ernie, Villaverde, Nicole, Facey, Jody Ann, Boschetti, Gilles, Giri, Mamta, Castillo-Martin, Mireia, Thin, Tin Htwe, Sharma, Yashoda, Chu, Jaime, Cho, Judy H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6737949/ https://www.ncbi.nlm.nih.gov/pubmed/31337664 http://dx.doi.org/10.1242/dmm.037432 |
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