Dynamic MAPK signaling activity underlies a transition from growth arrest to proliferation in Drosophila scribble mutant tumors

Human tumors exhibit plasticity and evolving capacity over time. It is difficult to study the mechanisms of how tumors change over time in human patients, in particular during the early stages when a few oncogenic cells are barely detectable. Here, we used a Drosophila tumor model caused by loss of...

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Detalles Bibliográficos
Autores principales: Ji, Tiantian, Zhang, Lina, Deng, Mingxi, Huang, Shengshuo, Wang, Ying, Pham, Tri Thanh, Smith, Andrew Alan, Sridhar, Varun, Cabernard, Clemens, Wang, Jiguang, Yan, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6737955/
https://www.ncbi.nlm.nih.gov/pubmed/31371383
http://dx.doi.org/10.1242/dmm.040147

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6737955/
https://www.ncbi.nlm.nih.gov/pubmed/31371383
http://dx.doi.org/10.1242/dmm.040147

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