EGFP insertional mutagenesis reveals multiple FXR2P fibrillar states with differing ribosome association in neurons

RNA-binding proteins (RBPs) function in higher-order assemblages such as RNA granules to regulate RNA localization and translation. The Fragile X homolog FXR2P is an RBP essential for formation of neuronal Fragile X granules that associate with axonal mRNA and ribosomes in the intact brain. However,...

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Detalles Bibliográficos
Autores principales: Stackpole, Emily E., Akins, Michael R., Ivshina, Maria, Murthy, Anastasia C., Fawzi, Nicolas L., Fallon, Justin R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6737979/
https://www.ncbi.nlm.nih.gov/pubmed/31434643
http://dx.doi.org/10.1242/bio.046383

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6737979/
https://www.ncbi.nlm.nih.gov/pubmed/31434643
http://dx.doi.org/10.1242/bio.046383

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