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EGFP insertional mutagenesis reveals multiple FXR2P fibrillar states with differing ribosome association in neurons
RNA-binding proteins (RBPs) function in higher-order assemblages such as RNA granules to regulate RNA localization and translation. The Fragile X homolog FXR2P is an RBP essential for formation of neuronal Fragile X granules that associate with axonal mRNA and ribosomes in the intact brain. However,...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Company of Biologists Ltd
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6737979/ https://www.ncbi.nlm.nih.gov/pubmed/31434643 http://dx.doi.org/10.1242/bio.046383 |