Role of Dach1 revealed using a novel inner ear-specific Dach1-knockdown mouse model

The Dach1 gene is expressed in the inner ear of normal mouse embryos in the area that differentiates into the cochlear stria vascularis (SV). We hypothesised that Dach1 downregulation in the inner ear would lead to SV dysplasia. However, because Dach1 knockout is embryonic lethal in mice, the role o...

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Detalles Bibliográficos
Autores principales: Miwa, Toru, Minoda, Ryosei, Ishikawa, Yoshihide, Kajii, Tomohito, Orita, Yorihisa, Ohyama, Takahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6737983/
https://www.ncbi.nlm.nih.gov/pubmed/31405829
http://dx.doi.org/10.1242/bio.043612

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6737983/
https://www.ncbi.nlm.nih.gov/pubmed/31405829
http://dx.doi.org/10.1242/bio.043612

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