Notch2 pathway mediates breast cancer cellular dormancy and mobilisation in bone and contributes to haematopoietic stem cell mimicry

BACKGROUND: Recurrence after >5-year disease-free survival affects one-fifth of breast cancer patients and is the clinical manifestation of cancer cell reactivation after persistent dormancy. METHODS: We investigated cellular dormancy in vitro and in vivo using breast cancer cell lines and cell a...

Descripción completa

Detalles Bibliográficos
Autores principales: Capulli, Mattia, Hristova, Dayana, Valbret, Zoé, Carys, Kashmala, Arjan, Ronak, Maurizi, Antonio, Masedu, Francesco, Cappariello, Alfredo, Rucci, Nadia, Teti, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6738045/
https://www.ncbi.nlm.nih.gov/pubmed/31239543
http://dx.doi.org/10.1038/s41416-019-0501-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6738045/
https://www.ncbi.nlm.nih.gov/pubmed/31239543
http://dx.doi.org/10.1038/s41416-019-0501-y

Ejemplares similares