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Notch2 pathway mediates breast cancer cellular dormancy and mobilisation in bone and contributes to haematopoietic stem cell mimicry

BACKGROUND: Recurrence after >5-year disease-free survival affects one-fifth of breast cancer patients and is the clinical manifestation of cancer cell reactivation after persistent dormancy. METHODS: We investigated cellular dormancy in vitro and in vivo using breast cancer cell lines and cell a...

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Detalles Bibliográficos
Autores principales:	Capulli, Mattia, Hristova, Dayana, Valbret, Zoé, Carys, Kashmala, Arjan, Ronak, Maurizi, Antonio, Masedu, Francesco, Cappariello, Alfredo, Rucci, Nadia, Teti, Anna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6738045/ https://www.ncbi.nlm.nih.gov/pubmed/31239543 http://dx.doi.org/10.1038/s41416-019-0501-y

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