The combination of complex karyotype subtypes and IGHV mutational status identifies new prognostic and predictive groups in chronic lymphocytic leukaemia

BACKGROUND: Complex karyotype (CK) is a heterogeneous category with a negative impact in chronic lymphocytic leukaemia (CLL). Our group has recently reported that CK patients with major structural abnormalities (i.e. CK2) are characterised by a worse prognosis, as compared to other lesions within CK...

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Detalles Bibliográficos
Autores principales: Visentin, Andrea, Bonaldi, Laura, Rigolin, Gian Matteo, Mauro, Francesca Romana, Martines, Annalisa, Frezzato, Federica, Imbergamo, Silvia, Scomazzon, Edoardo, Pravato, Stefano, Bardi, Maria Antonella, Cavallari, Maurizio, Volta, Eleonora, Cavazzini, Francesco, Nanni, Maurizio, Del Giudice, Ilaria, Facco, Monica, Guarini, Anna, Semenzato, Gianpietro, Foà, Robin, Cuneo, Antonio, Trentin, Livio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6738078/
https://www.ncbi.nlm.nih.gov/pubmed/31209327
http://dx.doi.org/10.1038/s41416-019-0502-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6738078/
https://www.ncbi.nlm.nih.gov/pubmed/31209327
http://dx.doi.org/10.1038/s41416-019-0502-x

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