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Detection of POLE Subtypes in High-Grade Endometrioid Carcinoma by BaseScope-ISH Assay

Objective: The identification of DNA polymerase epsilon (POLE) mutation subtypes in endometrial cancer is critical for molecular classification. The mutation of the POLE gene could only be detected by sequencing until now. We propose to validate and develop the feasibility of using BaseScope, an in...

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Detalles Bibliográficos
Autores principales: Yu, Shuangni, Shao, Huilin, Ban, Xinchao, Zhang, Hongkai, You, Yan, Zhou, Na, Mao, Xinxin, Zhao, He, Chen, Jie, Lu, Zhaohui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6738085/
https://www.ncbi.nlm.nih.gov/pubmed/31552169
http://dx.doi.org/10.3389/fonc.2019.00831