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Detection of POLE Subtypes in High-Grade Endometrioid Carcinoma by BaseScope-ISH Assay
Objective: The identification of DNA polymerase epsilon (POLE) mutation subtypes in endometrial cancer is critical for molecular classification. The mutation of the POLE gene could only be detected by sequencing until now. We propose to validate and develop the feasibility of using BaseScope, an in...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6738085/ https://www.ncbi.nlm.nih.gov/pubmed/31552169 http://dx.doi.org/10.3389/fonc.2019.00831 |