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Establishment and characterisation of a new patient-derived model of myxoid liposarcoma with acquired resistance to trabectedin
BACKGROUND: Myxoid liposarcoma is a histological subtype of liposarcoma particularly sensitive to trabectedin. In clinical use this drug does not cause cumulative toxicity, allowing prolonged treatment, generally until disease progression. No other effective therapies are available for trabectedin-r...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6738121/ https://www.ncbi.nlm.nih.gov/pubmed/31409911 http://dx.doi.org/10.1038/s41416-019-0550-2 |