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Down Regulation of c-FLIP(L) Enhance PD-1 Blockade Efficacy in B16 Melanoma

Immune checkpoint blockade of programmed cell death protein 1 (PD-1) had an impressive long-lasting effect in a portion of advanced-stage melanoma patients, however, this therapy failed to induce responses in several patients; how to increase the objective response rate is very important. Cellular F...

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Detalles Bibliográficos
Autores principales: Wang, Yao, Li, Jing-jing, Ba, Hong-jun, Wang, Ke-feng, Wen, Xi-zhi, Li, Dan-dan, Zhu, Xiao-feng, Zhang, Xiao-shi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6738195/
https://www.ncbi.nlm.nih.gov/pubmed/31552181
http://dx.doi.org/10.3389/fonc.2019.00857