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Down Regulation of c-FLIP(L) Enhance PD-1 Blockade Efficacy in B16 Melanoma
Immune checkpoint blockade of programmed cell death protein 1 (PD-1) had an impressive long-lasting effect in a portion of advanced-stage melanoma patients, however, this therapy failed to induce responses in several patients; how to increase the objective response rate is very important. Cellular F...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6738195/ https://www.ncbi.nlm.nih.gov/pubmed/31552181 http://dx.doi.org/10.3389/fonc.2019.00857 |