Exercise-Induced Acute Kidney Injury in a Police Officer with Hereditary Renal Hypouricemia

Hereditary renal hypouricemia is characterized by hypouricemia with hyper-uric acid clearance due to a defect in renal tubular transport. Patients with hereditary renal hypouricemia have a higher risk of exercise-induced acute kidney injury (EAKI) and reduced kidney function. Although the best preve...

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Autores principales: Shimizu, Yoshio, Wakabayashi, Keiichi, Totsuka, Ayako, Hayashi, Yoko, Nitta, Shusaku, Hara, Kazuaki, Akira, Maiko, Tomino, Yasuhiko, Suzuki, Yusuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6738254/
https://www.ncbi.nlm.nih.gov/pubmed/31602378
http://dx.doi.org/10.1159/000501877
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author Shimizu, Yoshio
Wakabayashi, Keiichi
Totsuka, Ayako
Hayashi, Yoko
Nitta, Shusaku
Hara, Kazuaki
Akira, Maiko
Tomino, Yasuhiko
Suzuki, Yusuke
author_facet Shimizu, Yoshio
Wakabayashi, Keiichi
Totsuka, Ayako
Hayashi, Yoko
Nitta, Shusaku
Hara, Kazuaki
Akira, Maiko
Tomino, Yasuhiko
Suzuki, Yusuke
author_sort Shimizu, Yoshio
collection PubMed
description Hereditary renal hypouricemia is characterized by hypouricemia with hyper-uric acid clearance due to a defect in renal tubular transport. Patients with hereditary renal hypouricemia have a higher risk of exercise-induced acute kidney injury (EAKI) and reduced kidney function. Although the best preventive measure is avoiding exercise, there are many kinds of jobs that require occupational exercise. A 27-year-old male police officer suffered from stage 3 AKI after performing a 20-m multistage shuttle run test. His mother had previously been diagnosed as having renal hypouricemia at another facility. The patient had reported having hypouricemia during a health check at a previous police station, but his serum uric acid concentration was within the normal range at our hospital. After treatment, he recovered from EAKI and exhibited low serum uric acid and hyper-uric acid clearance. Since the patient desired to continue his career requiring strenuous exercise, it was difficult to establish a preventive plan against the recurrence of EAKI. Patients with hereditary renal hypouricemia who must undergo strenuous occupational anaerobic exercise are at higher risk of developing EAKI than other workers. The risks of EAKI among patients with hypouricemia should be considered when undergoing physical occupational training.
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spelling pubmed-67382542019-10-10 Exercise-Induced Acute Kidney Injury in a Police Officer with Hereditary Renal Hypouricemia Shimizu, Yoshio Wakabayashi, Keiichi Totsuka, Ayako Hayashi, Yoko Nitta, Shusaku Hara, Kazuaki Akira, Maiko Tomino, Yasuhiko Suzuki, Yusuke Case Rep Nephrol Dial Case Report Hereditary renal hypouricemia is characterized by hypouricemia with hyper-uric acid clearance due to a defect in renal tubular transport. Patients with hereditary renal hypouricemia have a higher risk of exercise-induced acute kidney injury (EAKI) and reduced kidney function. Although the best preventive measure is avoiding exercise, there are many kinds of jobs that require occupational exercise. A 27-year-old male police officer suffered from stage 3 AKI after performing a 20-m multistage shuttle run test. His mother had previously been diagnosed as having renal hypouricemia at another facility. The patient had reported having hypouricemia during a health check at a previous police station, but his serum uric acid concentration was within the normal range at our hospital. After treatment, he recovered from EAKI and exhibited low serum uric acid and hyper-uric acid clearance. Since the patient desired to continue his career requiring strenuous exercise, it was difficult to establish a preventive plan against the recurrence of EAKI. Patients with hereditary renal hypouricemia who must undergo strenuous occupational anaerobic exercise are at higher risk of developing EAKI than other workers. The risks of EAKI among patients with hypouricemia should be considered when undergoing physical occupational training. S. Karger AG 2019-07-29 /pmc/articles/PMC6738254/ /pubmed/31602378 http://dx.doi.org/10.1159/000501877 Text en Copyright © 2019 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc/4.0/ This article is licensed under the Creative Commons Attribution-NonCommercial-4.0 International License (CC BY-NC) (http://www.karger.com/Services/OpenAccessLicense). Usage and distribution for commercial purposes requires written permission.
spellingShingle Case Report
Shimizu, Yoshio
Wakabayashi, Keiichi
Totsuka, Ayako
Hayashi, Yoko
Nitta, Shusaku
Hara, Kazuaki
Akira, Maiko
Tomino, Yasuhiko
Suzuki, Yusuke
Exercise-Induced Acute Kidney Injury in a Police Officer with Hereditary Renal Hypouricemia
title Exercise-Induced Acute Kidney Injury in a Police Officer with Hereditary Renal Hypouricemia
title_full Exercise-Induced Acute Kidney Injury in a Police Officer with Hereditary Renal Hypouricemia
title_fullStr Exercise-Induced Acute Kidney Injury in a Police Officer with Hereditary Renal Hypouricemia
title_full_unstemmed Exercise-Induced Acute Kidney Injury in a Police Officer with Hereditary Renal Hypouricemia
title_short Exercise-Induced Acute Kidney Injury in a Police Officer with Hereditary Renal Hypouricemia
title_sort exercise-induced acute kidney injury in a police officer with hereditary renal hypouricemia
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6738254/
https://www.ncbi.nlm.nih.gov/pubmed/31602378
http://dx.doi.org/10.1159/000501877
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