Exercise-Induced Acute Kidney Injury in a Police Officer with Hereditary Renal Hypouricemia
Hereditary renal hypouricemia is characterized by hypouricemia with hyper-uric acid clearance due to a defect in renal tubular transport. Patients with hereditary renal hypouricemia have a higher risk of exercise-induced acute kidney injury (EAKI) and reduced kidney function. Although the best preve...
Autores principales: | , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
S. Karger AG
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6738254/ https://www.ncbi.nlm.nih.gov/pubmed/31602378 http://dx.doi.org/10.1159/000501877 |
_version_ | 1783450801179459584 |
---|---|
author | Shimizu, Yoshio Wakabayashi, Keiichi Totsuka, Ayako Hayashi, Yoko Nitta, Shusaku Hara, Kazuaki Akira, Maiko Tomino, Yasuhiko Suzuki, Yusuke |
author_facet | Shimizu, Yoshio Wakabayashi, Keiichi Totsuka, Ayako Hayashi, Yoko Nitta, Shusaku Hara, Kazuaki Akira, Maiko Tomino, Yasuhiko Suzuki, Yusuke |
author_sort | Shimizu, Yoshio |
collection | PubMed |
description | Hereditary renal hypouricemia is characterized by hypouricemia with hyper-uric acid clearance due to a defect in renal tubular transport. Patients with hereditary renal hypouricemia have a higher risk of exercise-induced acute kidney injury (EAKI) and reduced kidney function. Although the best preventive measure is avoiding exercise, there are many kinds of jobs that require occupational exercise. A 27-year-old male police officer suffered from stage 3 AKI after performing a 20-m multistage shuttle run test. His mother had previously been diagnosed as having renal hypouricemia at another facility. The patient had reported having hypouricemia during a health check at a previous police station, but his serum uric acid concentration was within the normal range at our hospital. After treatment, he recovered from EAKI and exhibited low serum uric acid and hyper-uric acid clearance. Since the patient desired to continue his career requiring strenuous exercise, it was difficult to establish a preventive plan against the recurrence of EAKI. Patients with hereditary renal hypouricemia who must undergo strenuous occupational anaerobic exercise are at higher risk of developing EAKI than other workers. The risks of EAKI among patients with hypouricemia should be considered when undergoing physical occupational training. |
format | Online Article Text |
id | pubmed-6738254 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | S. Karger AG |
record_format | MEDLINE/PubMed |
spelling | pubmed-67382542019-10-10 Exercise-Induced Acute Kidney Injury in a Police Officer with Hereditary Renal Hypouricemia Shimizu, Yoshio Wakabayashi, Keiichi Totsuka, Ayako Hayashi, Yoko Nitta, Shusaku Hara, Kazuaki Akira, Maiko Tomino, Yasuhiko Suzuki, Yusuke Case Rep Nephrol Dial Case Report Hereditary renal hypouricemia is characterized by hypouricemia with hyper-uric acid clearance due to a defect in renal tubular transport. Patients with hereditary renal hypouricemia have a higher risk of exercise-induced acute kidney injury (EAKI) and reduced kidney function. Although the best preventive measure is avoiding exercise, there are many kinds of jobs that require occupational exercise. A 27-year-old male police officer suffered from stage 3 AKI after performing a 20-m multistage shuttle run test. His mother had previously been diagnosed as having renal hypouricemia at another facility. The patient had reported having hypouricemia during a health check at a previous police station, but his serum uric acid concentration was within the normal range at our hospital. After treatment, he recovered from EAKI and exhibited low serum uric acid and hyper-uric acid clearance. Since the patient desired to continue his career requiring strenuous exercise, it was difficult to establish a preventive plan against the recurrence of EAKI. Patients with hereditary renal hypouricemia who must undergo strenuous occupational anaerobic exercise are at higher risk of developing EAKI than other workers. The risks of EAKI among patients with hypouricemia should be considered when undergoing physical occupational training. S. Karger AG 2019-07-29 /pmc/articles/PMC6738254/ /pubmed/31602378 http://dx.doi.org/10.1159/000501877 Text en Copyright © 2019 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc/4.0/ This article is licensed under the Creative Commons Attribution-NonCommercial-4.0 International License (CC BY-NC) (http://www.karger.com/Services/OpenAccessLicense). Usage and distribution for commercial purposes requires written permission. |
spellingShingle | Case Report Shimizu, Yoshio Wakabayashi, Keiichi Totsuka, Ayako Hayashi, Yoko Nitta, Shusaku Hara, Kazuaki Akira, Maiko Tomino, Yasuhiko Suzuki, Yusuke Exercise-Induced Acute Kidney Injury in a Police Officer with Hereditary Renal Hypouricemia |
title | Exercise-Induced Acute Kidney Injury in a Police Officer with Hereditary Renal Hypouricemia |
title_full | Exercise-Induced Acute Kidney Injury in a Police Officer with Hereditary Renal Hypouricemia |
title_fullStr | Exercise-Induced Acute Kidney Injury in a Police Officer with Hereditary Renal Hypouricemia |
title_full_unstemmed | Exercise-Induced Acute Kidney Injury in a Police Officer with Hereditary Renal Hypouricemia |
title_short | Exercise-Induced Acute Kidney Injury in a Police Officer with Hereditary Renal Hypouricemia |
title_sort | exercise-induced acute kidney injury in a police officer with hereditary renal hypouricemia |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6738254/ https://www.ncbi.nlm.nih.gov/pubmed/31602378 http://dx.doi.org/10.1159/000501877 |
work_keys_str_mv | AT shimizuyoshio exerciseinducedacutekidneyinjuryinapoliceofficerwithhereditaryrenalhypouricemia AT wakabayashikeiichi exerciseinducedacutekidneyinjuryinapoliceofficerwithhereditaryrenalhypouricemia AT totsukaayako exerciseinducedacutekidneyinjuryinapoliceofficerwithhereditaryrenalhypouricemia AT hayashiyoko exerciseinducedacutekidneyinjuryinapoliceofficerwithhereditaryrenalhypouricemia AT nittashusaku exerciseinducedacutekidneyinjuryinapoliceofficerwithhereditaryrenalhypouricemia AT harakazuaki exerciseinducedacutekidneyinjuryinapoliceofficerwithhereditaryrenalhypouricemia AT akiramaiko exerciseinducedacutekidneyinjuryinapoliceofficerwithhereditaryrenalhypouricemia AT tominoyasuhiko exerciseinducedacutekidneyinjuryinapoliceofficerwithhereditaryrenalhypouricemia AT suzukiyusuke exerciseinducedacutekidneyinjuryinapoliceofficerwithhereditaryrenalhypouricemia |