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Triple Trouble: A Case of Multiple Resistance Mechanisms after First Generation EGFR-TKI in NSCLC

Epidermal growth factor receptor (EGFR)-targeted therapy has become standard of care in advanced stages EGFR-mutant non-small cell lung cancer. Acquired resistance to first-line EGFR-tyrosine kinase inhibitor (TKI) and subsequent disease progression is a common problem and mostly due to a secondary...

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Detalles Bibliográficos
Autores principales: Ralki, Mike, Maes, Brigitte, Pat, Karin, Wynants, Jokke, Cuppens, Kristof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6738260/
https://www.ncbi.nlm.nih.gov/pubmed/31543779
http://dx.doi.org/10.1159/000502214