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The arrival of biosimilar monoclonal antibodies in oncology: clinical studies for trastuzumab biosimilars

The monoclonal antibody trastuzumab (Herceptin®), which targets the human epidermal growth factor receptor 2 (HER2), is approved for the treatment of early breast and advanced breast and gastric cancer in which HER2 is overexpressed. Several biosimilar versions of trastuzumab are expected to enter t...

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Detalles Bibliográficos
Autores principales: Barbier, Liese, Declerck, Paul, Simoens, Steven, Neven, Patrick, Vulto, Arnold G., Huys, Isabelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6738325/
https://www.ncbi.nlm.nih.gov/pubmed/31257362
http://dx.doi.org/10.1038/s41416-019-0480-z