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Inhibition of de novo ceramide biosynthesis affects aging phenotype in an in vitro model of neuronal senescence
Although aging is considered to be an unavoidable event, recent experimental evidence suggests that the process can be counteracted. Intracellular calcium (Ca(2+)(i)) dyshomeostasis, mitochondrial dysfunction, oxidative stress, and lipid dysregulation are critical factors that contribute to senescen...
| Autores principales: | , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Impact Journals
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6738398/ https://www.ncbi.nlm.nih.gov/pubmed/31467258 http://dx.doi.org/10.18632/aging.102191 |