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Attenuated BK channel function promotes overactive bladder in a rat model of obesity
Overactive bladder (OAB) is mostly observed in obese individuals, and is associated with enhanced excitability and contractility of the detrusor smooth muscle (DSM). Large-conductance voltage- and Ca(2+)-activated K(+) (BK) channels reduce the excitability and contractility of the DSM. We tested whe...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6738405/ https://www.ncbi.nlm.nih.gov/pubmed/31480021 http://dx.doi.org/10.18632/aging.102182 |