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Down-regulation of Cav1.3 in auditory pathway promotes age-related hearing loss by enhancing calcium-mediated oxidative stress in male mice

In this study, age related Cav1.3 expression in cochlea and auditory cortex of C57BL/6J male mice was evaluated. It was found that the expression of Cav1.3 in cochlea decreased with aging whereas this phenomenon was not observed in neuron of auditory cortex. The correlation between decreased express...

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Detalles Bibliográficos
Autores principales: Qi, Fan, Zhang, Rongsheng, Chen, Jin, Zhao, Fei, Sun, Yanbo, Du, Zhihui, Bing, Dan, Li, Pengjun, Shao, Shengli, Zhu, Hongmei, Chu, Hanqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6738406/
https://www.ncbi.nlm.nih.gov/pubmed/31425146
http://dx.doi.org/10.18632/aging.102203