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Down-regulation of Cav1.3 in auditory pathway promotes age-related hearing loss by enhancing calcium-mediated oxidative stress in male mice
In this study, age related Cav1.3 expression in cochlea and auditory cortex of C57BL/6J male mice was evaluated. It was found that the expression of Cav1.3 in cochlea decreased with aging whereas this phenomenon was not observed in neuron of auditory cortex. The correlation between decreased express...
Autores principales: | Qi, Fan, Zhang, Rongsheng, Chen, Jin, Zhao, Fei, Sun, Yanbo, Du, Zhihui, Bing, Dan, Li, Pengjun, Shao, Shengli, Zhu, Hongmei, Chu, Hanqi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6738406/ https://www.ncbi.nlm.nih.gov/pubmed/31425146 http://dx.doi.org/10.18632/aging.102203 |
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