Cortical neurons develop a senescence-like phenotype promoted by dysfunctional autophagy

Senescent cells accumulate in various tissues and organs with aging altering surrounding tissue due to an active secretome, and at least in mice their elimination extends healthy lifespan and ameliorates several chronic diseases. Whether all cell types senesce, including post-mitotic cells, has been...

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Detalles Bibliográficos
Autores principales: Moreno-Blas, Daniel, Gorostieta-Salas, Elisa, Pommer-Alba, Alexander, Muciño-Hernández, Gabriel, Gerónimo-Olvera, Cristian, Maciel-Barón, Luis Angel, Konigsberg, Mina, Massieu, Lourdes, Castro-Obregón, Susana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6738425/
https://www.ncbi.nlm.nih.gov/pubmed/31469660
http://dx.doi.org/10.18632/aging.102181

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6738425/
https://www.ncbi.nlm.nih.gov/pubmed/31469660
http://dx.doi.org/10.18632/aging.102181

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