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Role and mechanism of cardiac insulin resistance in occurrence of heart failure caused by myocardial hypertrophy

Cardiac insulin resistance plays an important role in the development of heart failure, but the underlying mechanisms remain unclear. Here, we found that hypertrophic hearts exhibit normal cardiac glucose oxidation rates, but reduced fatty acid oxidation rates, compared to Sham controls under basal...

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Detalles Bibliográficos
Autores principales: Zheng, Liling, Li, Bingbing, Lin, Sihuang, Chen, Liangcai, Li, Hongmu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6738426/
https://www.ncbi.nlm.nih.gov/pubmed/31461405
http://dx.doi.org/10.18632/aging.102212