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Cinobufagin Induces Cell Cycle Arrest at the G2/M Phase and Promotes Apoptosis in Malignant Melanoma Cells

Emerging evidence has shown that cinobufagin, as an active ingredient of Venenum Bufonis, inhibits tumor development. The aim of this study was to investigate the inhibitory effects of cinobufagin on A375 human malignant melanoma cells. MTT and colony formation assays showed that cinobufagin signifi...

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Detalles Bibliográficos
Autores principales: Pan, Zhaohai, Zhang, Xin, Yu, Pengfei, Chen, Xiaoyu, Lu, Peng, Li, Minjing, Liu, Xiaona, Li, Zhipeng, Wei, Fei, Wang, Kejun, Zheng, Qiusheng, Li, Defang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6738445/
https://www.ncbi.nlm.nih.gov/pubmed/31552178
http://dx.doi.org/10.3389/fonc.2019.00853