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The absence of interleukin 10 affects the morphology, differentiation, granule content and the production of cryptidin-4 in Paneth cells in mice

Paneth cells (PCs) are specialized epithelial cells of the small bowel that contain multiple secretory granules filled with antimicrobial peptides and trophic factors, which are essential for the control of the microorganisms growth and maintaining intestinal integrity. Alterations in their function...

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Detalles Bibliográficos
Autores principales: Berkowitz, Loni, Pardo-Roa, Catalina, Ramírez, Gigliola, Vallejos, Omar P., Sebastián, Valentina P., Riedel, Claudia A., Álvarez-Lobos, Manuel, Bueno, Susan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6738610/
https://www.ncbi.nlm.nih.gov/pubmed/31509557
http://dx.doi.org/10.1371/journal.pone.0221618