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A benchmark of computational CRISPR-Cas9 guide design methods
The popularity of CRISPR-based gene editing has resulted in an abundance of tools to design CRISPR-Cas9 guides. This is also driven by the fact that designing highly specific and efficient guides is a crucial, but not trivial, task in using CRISPR for gene editing. Here, we thoroughly analyse the pe...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6738662/ https://www.ncbi.nlm.nih.gov/pubmed/31465436 http://dx.doi.org/10.1371/journal.pcbi.1007274 |