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SSD1 suppresses phenotypes induced by the lack of Elongator-dependent tRNA modifications

The Elongator complex promotes formation of 5-methoxycarbonylmethyl (mcm(5)) and 5-carbamoylmethyl (ncm(5)) side-chains on uridines at the wobble position of cytosolic eukaryotic tRNAs. In all eukaryotic organisms tested to date, the inactivation of Elongator not only leads to the lack of mcm(5)/ncm...

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Detalles Bibliográficos
Autores principales: Xu, Fu, Byström, Anders S., Johansson, Marcus J. O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6738719/
https://www.ncbi.nlm.nih.gov/pubmed/31465447
http://dx.doi.org/10.1371/journal.pgen.1008117