Cargando…
SSD1 suppresses phenotypes induced by the lack of Elongator-dependent tRNA modifications
The Elongator complex promotes formation of 5-methoxycarbonylmethyl (mcm(5)) and 5-carbamoylmethyl (ncm(5)) side-chains on uridines at the wobble position of cytosolic eukaryotic tRNAs. In all eukaryotic organisms tested to date, the inactivation of Elongator not only leads to the lack of mcm(5)/ncm...
Autores principales: | Xu, Fu, Byström, Anders S., Johansson, Marcus J. O. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6738719/ https://www.ncbi.nlm.nih.gov/pubmed/31465447 http://dx.doi.org/10.1371/journal.pgen.1008117 |
Ejemplares similares
-
SSD1 modifies phenotypes of Elongator mutants
por: Xu, Fu, et al.
Publicado: (2019) -
Defects in tRNA Modification Associated with Neurological and Developmental Dysfunctions in Caenorhabditis elegans Elongator Mutants
por: Chen, Changchun, et al.
Publicado: (2009) -
Elongator function in tRNA wobble uridine modification is conserved between yeast and plants
por: Mehlgarten, Constance, et al.
Publicado: (2010) -
Identification of factors that promote biogenesis of tRNA(CGA)(Ser)
por: Xu, Fu, et al.
Publicado: (2018) -
Elongator Complex Influences Telomeric Gene Silencing and DNA Damage Response by Its Role in Wobble Uridine tRNA Modification
por: Chen, Changchun, et al.
Publicado: (2011)