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Circulating B Cells With Memory and Antibody-Secreting Phenotypes Are Detectable in Pediatric Kidney Transplant Recipients Before the Development of Antibody-Mediated Rejection

Development of anti–human leukocyte antigen donor-specific antibodies (DSAs) is associated with antibody-mediated rejection (AMR) and reduced allograft survival in kidney transplant recipients. Whether changes in circulating lymphocytes anticipate DSA or AMR development is unclear. METHODS. We used...

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Detalles Bibliográficos
Autores principales: Fischman, Clara, Fribourg, Miguel, Fabrizio, Ginevri, Cioni, Michela, Comoli, Patrizia, Nocera, Arcangelo, Cardillo, Massimo, Cantarelli, Chiara, Gallon, Lorenzo, Petrosyan, Astgik, Da Sacco, Stefano, Perin, Laura, Cravedi, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6739044/
https://www.ncbi.nlm.nih.gov/pubmed/31579809
http://dx.doi.org/10.1097/TXD.0000000000000914