Mitochondrial protein import is regulated by p17/PERMIT to mediate lipid metabolism and cellular stress

How lipid metabolism is regulated at the outer mitochondrial membrane (OMM) for transducing stress signaling remains largely unknown. We show here that this process is controlled by trafficking of ceramide synthase 1 (CerS1) from the endoplasmic reticulum (ER) to the OMM by a previously uncharacteri...

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Detalles Bibliográficos
Autores principales: Oleinik, Natalia, Kim, Jisun, Roth, Braden M., Selvam, Shanmugam Panneer, Gooz, Monika, Johnson, Roger H., Lemasters, John J., Ogretmen, Besim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6739097/
https://www.ncbi.nlm.nih.gov/pubmed/31535025
http://dx.doi.org/10.1126/sciadv.aax1978

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6739097/
https://www.ncbi.nlm.nih.gov/pubmed/31535025
http://dx.doi.org/10.1126/sciadv.aax1978

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