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Mitochondrial protein import is regulated by p17/PERMIT to mediate lipid metabolism and cellular stress
How lipid metabolism is regulated at the outer mitochondrial membrane (OMM) for transducing stress signaling remains largely unknown. We show here that this process is controlled by trafficking of ceramide synthase 1 (CerS1) from the endoplasmic reticulum (ER) to the OMM by a previously uncharacteri...
Autores principales: | Oleinik, Natalia, Kim, Jisun, Roth, Braden M., Selvam, Shanmugam Panneer, Gooz, Monika, Johnson, Roger H., Lemasters, John J., Ogretmen, Besim |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6739097/ https://www.ncbi.nlm.nih.gov/pubmed/31535025 http://dx.doi.org/10.1126/sciadv.aax1978 |
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