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Combinatorial Treatment Using Umbilical Cord Perivascular Cells and Aβ Clearance Rescues Vascular Function Following Transient Hypertension in a Rat Model of Alzheimer Disease

Transient hypertension is a risk factor for Alzheimer disease (AD), but the effects of this interaction on brain vasculature are understudied. Addressing vascular pathology is a promising avenue to potentiate the efficacy of treatments for AD. We used arterial spin labeling magnetic resonance imagin...

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Detalles Bibliográficos
Autores principales: Bazzigaluppi, Paolo, Beckett, Tina L., Koletar, Margaret M., Hill, Mary E., Lai, Aaron, Trivedi, Arunachala, Thomason, Lynsie, Dorr, Adrienne, Gallagher, Denis, Librach, Clifford L., Joo, Illsung L., McLaurin, JoAnne, Stefanovic, Bojana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott, Williams & Wilkins 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6739147/
https://www.ncbi.nlm.nih.gov/pubmed/31476904
http://dx.doi.org/10.1161/HYPERTENSIONAHA.119.13187