Cargando…

Combinatorial Treatment Using Umbilical Cord Perivascular Cells and Aβ Clearance Rescues Vascular Function Following Transient Hypertension in a Rat Model of Alzheimer Disease

Transient hypertension is a risk factor for Alzheimer disease (AD), but the effects of this interaction on brain vasculature are understudied. Addressing vascular pathology is a promising avenue to potentiate the efficacy of treatments for AD. We used arterial spin labeling magnetic resonance imagin...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bazzigaluppi, Paolo, Beckett, Tina L., Koletar, Margaret M., Hill, Mary E., Lai, Aaron, Trivedi, Arunachala, Thomason, Lynsie, Dorr, Adrienne, Gallagher, Denis, Librach, Clifford L., Joo, Illsung L., McLaurin, JoAnne, Stefanovic, Bojana
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott, Williams & Wilkins 2019
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6739147/ https://www.ncbi.nlm.nih.gov/pubmed/31476904 http://dx.doi.org/10.1161/HYPERTENSIONAHA.119.13187

Ejemplares similares

Early neurovascular dysfunction in a transgenic rat model of Alzheimer’s disease
por: Joo, Illsung L., et al.
Publicado: (2017)

Frequency selective neuronal modulation triggers spreading depolarizations in the rat endothelin-1 model of stroke
por: Bazzigaluppi, Paolo, et al.
Publicado: (2021)

Regional differences in Alzheimer’s disease pathology confound behavioural rescue after amyloid-β attenuation
por: Morrone, Christopher D, et al.
Publicado: (2020)

Refinement of a chronic cranial window implant in the rat for longitudinal in vivo two–photon fluorescence microscopy of neurovascular function
por: Koletar, Margaret M., et al.
Publicado: (2019)

Attenuation of tonic inhibition prevents chronic neurovascular impairments in a Thy1-ChR2 mouse model of repeated, mild traumatic brain injury
por: Mester, James R, et al.
Publicado: (2021)

Oophorectomy Reduces Estradiol Levels and Long-Term Spontaneous Neurovascular Recovery in a Female Rat Model of Focal Ischemic Stroke
por: Bazzigaluppi, Paolo, et al.
Publicado: (2018)

Neurogliovascular dysfunction in a model of repeated traumatic brain injury
por: Adams, Conner, et al.
Publicado: (2018)

Compromised Cortical-Hippocampal Network Function From Transient Hypertension: Linking Mid-Life Hypertension to Late Life Dementia Risk
por: Lai, Aaron Y., et al.
Publicado: (2022)

In Vitro Differentiation of First Trimester Human Umbilical Cord Perivascular Cells into Contracting Cardiomyocyte-Like Cells
por: Szaraz, Peter, et al.
Publicado: (2016)

Effects of Neurotrophic Support and Amyloid-Targeted Combined Therapy on Adult Hippocampal Neurogenesis in a Transgenic Model of Alzheimer's Disease
por: Morrone, Christopher D., et al.
Publicado: (2016)

First trimester human umbilical cord perivascular cells (HUCPVC) modulate the kynurenine pathway and glutamate neurotransmission in an LPS-induced mouse model of neuroinflammation
por: Siddiqui, Fyyaz, et al.
Publicado: (2023)

In vitro generation of Sertoli-like and haploid spermatid-like cells from human umbilical cord perivascular cells
por: Shlush, Ekaterina, et al.
Publicado: (2017)

Combination human umbilical cord perivascular and endothelial colony forming cell therapy for ischemic cardiac injury
por: Iqbal, Farwah, et al.
Publicado: (2023)

Hungry Neurons: Metabolic Insights on Seizure Dynamics
por: Bazzigaluppi, Paolo, et al.
Publicado: (2017)

3D morphological analysis of the mouse cerebral vasculature: Comparison of in vivo and ex vivo methods
por: Steinman, Joe, et al.
Publicado: (2017)

Interaction between therapeutic interventions for Alzheimer’s disease and physiological Aβ clearance mechanisms
por: Morrone, Christopher D., et al.
Publicado: (2015)

In Vivo Neocortical [K]o Modulation by Targeted Stimulation of Astrocytes
por: EbrahimAmini, Azin, et al.
Publicado: (2021)

Lymphatic Clearance of the Brain: Perivascular, Paravascular and Significance for Neurodegenerative Diseases
por: Bakker, Erik N. T. P., et al.
Publicado: (2016)

The Association between Glymphatic System and Perivascular Macrophages in Brain Waste Clearance
por: Kaur, Jasleen, et al.
Publicado: (2023)

Venular amyloid accumulation in transgenic Fischer 344 Alzheimer’s disease rats
por: Bishay, J., et al.
Publicado: (2022)

Perivascular spaces and brain waste clearance systems: relevance for neurodegenerative and cerebrovascular pathology
por: Gouveia-Freitas, Kaylene, et al.
Publicado: (2021)

Interstitial Fluid Flows along Perivascular and Adventitial Clearances around Neurovascular Bundles
por: Kong, Yiya, et al.
Publicado: (2022)

Development and Characterization of Alkaline Phosphatase-Positive Human Umbilical Cord Perivascular Cells
por: Nonoyama, Shun, et al.
Publicado: (2021)

Cerebral amyloid angiopathy aggravates perivascular clearance impairment in an Alzheimer’s disease mouse model
por: Kim, Shin Heun, et al.
Publicado: (2020)

Dispersion as a waste-clearance mechanism in flow through penetrating perivascular spaces in the brain
por: Troyetsky, Daniel E., et al.
Publicado: (2021)

Expression of Ion Channels in Perivascular Stem Cells derived from Human Umbilical Cords
por: Kim, Eunbi, et al.
Publicado: (2017)

MRI of Whole Rat Brain Perivascular Network Reveals Role for Ventricles in Brain Waste Clearance
por: Magdoom, Kulam Najmudeen, et al.
Publicado: (2019)

Differentiation and migration properties of human foetal umbilical cord perivascular cells: potential for lung repair
por: Montemurro, Tiziana, et al.
Publicado: (2011)

Author Correction: Dispersion as a waste-clearance mechanism in flow through penetrating perivascular spaces in the brain
por: Troyetsky, Daniel E., et al.
Publicado: (2021)

Heparanase overexpression impedes perivascular clearance of amyloid-β from murine brain: relevance to Alzheimer’s disease
por: Zhang, Xiao, et al.
Publicado: (2021)

Non-invasive imaging of CSF-mediated brain clearance pathways via assessment of perivascular fluid movement with diffusion tensor MRI
por: Harrison, Ian F, et al.
Publicado: (2018)

Silencing BRE Expression in Human Umbilical Cord Perivascular (HUCPV) Progenitor Cells Accelerates Osteogenic and Chondrogenic Differentiation
por: Chen, Elve, et al.
Publicado: (2013)

Umbilical cord artery-derived perivascular stem cells for treatment of ovarian failure through CD146 signaling
por: Xu, Lu, et al.
Publicado: (2022)

Serum- and xeno-free culture of human umbilical cord perivascular cells for pediatric heart valve tissue engineering
por: Parvin Nejad, Shouka, et al.
Publicado: (2023)

Low‐dose brimonidine for relief of ocular redness: integrated analysis of four clinical trials
por: Ackerman, Stacey L, et al.
Publicado: (2018)

The Medicaid Cost of Palivizumab
por: Ambrose, Christopher S., et al.
Publicado: (2015)

Rapid Nanoparticle Synthesis by Magnetic and Microwave Heating
por: Chikan, Viktor, et al.
Publicado: (2016)

Mechanisms of Amyloid-Beta Peptide Uptake by Neurons: The Role of Lipid Rafts and Lipid Raft-Associated Proteins
por: Lai, Aaron Y., et al.
Publicado: (2010)

Autophagy in the Immunosuppressive Perivascular Microenvironment of Glioblastoma
por: Molina, Maria L., et al.
Publicado: (2019)

CD146(+) Human Umbilical Cord Perivascular Cells Maintain Stemness under Hypoxia and as a Cell Source for Skeletal Regeneration
por: Tsang, Wing Pui, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_27cqh285h2oob3r0qtrl99k6t0