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Proteases facilitate the endosomal escape of porcine epidemic diarrhea virus during entry into host cells

Exogenous and endogenous proteases play important roles in porcine epidemic diarrhea virus (PEDV) entry and replication. The roles of proteases in the viral endosomal escape and replication using trypsin (KD) or elastase (AA)-adapted US PEDV strains were studied. While PEDV KD and AA require differe...

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Detalles Bibliográficos
Autores principales: Oh, Changin, Kim, Yunjeong, Chang, Kyeong-Ok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6739164/
https://www.ncbi.nlm.nih.gov/pubmed/31445102
http://dx.doi.org/10.1016/j.virusres.2019.197730