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One-bead one-compound combinatorial library derived targeting ligands for detection and treatment of oral squamous cancer

Oral squamous cancers (OSC) are hallmarked by poor prognosis, delayed clinical detection, and a lack of defined, characteristic biomarkers. By screening combinatorial one-bead one-compound (OBOC) peptide libraries against oral squamous cancer cell lines, two cyclic peptide ligands, LLY12 and LLY13 w...

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Detalles Bibliográficos
Autores principales: Yang, Fan, Xiao, Wenwu, Liu, Yanlei, Liu, Ruiwu, Kramer, Randall, Li, Xiaocen, Ajena, Yousif, Baehr, Christopher M., Rojalin, Tatu, Zhang, Hongyong, Lam, Kit S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6739215/
https://www.ncbi.nlm.nih.gov/pubmed/31534631
http://dx.doi.org/10.18632/oncotarget.27189