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Fak silencing impairs osteogenic differentiation of bone mesenchymal stem cells induced by uniaxial mechanical stretch

BACKGROUND/PURPOSE: Mechanical stretch plays a key role in promoting proliferation and differentiation of bone marrow mesenchymal stem cells (BMSCs) in distraction osteogenesis (DO). A better understanding of how the extracellular biomechanical stimulation is transferred to intracellular signal expr...

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Detalles Bibliográficos
Autores principales: Hu, Pei, Zhu, Xiaowen, Zhao, Chuang, Hu, Jing, Luo, En, Ye, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Association for Dental Sciences of the Republic of China 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6739265/
https://www.ncbi.nlm.nih.gov/pubmed/31528249
http://dx.doi.org/10.1016/j.jds.2019.03.001