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Resveratrol antagonizes thyroid hormone-induced expression of checkpoint and proliferative genes in oral cancer cells

BACKGROUND/PURPOSE: Dysregulation of cell cycle checkpoint control may lead to the independence of growth regulating signals. Checkpoint protein such as the PD-1/PD-L1 immune checkpoint involving tumor cells and host immune defense lymphocytes is a well-studied therapeutic target in oncology. Acting...

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Detalles Bibliográficos
Autores principales: Lin, Chia-Cheng, Chin, Yu-Tang, Shih, Ya-Jung, Chen, Yi-Ru, Chung, Yao-Yu, Lin, Chi-Yu, Hsiung, Chao-Nan, Whang-Peng, Jacqueline, Lee, Sheng-Yang, Lin, Hung-Yun, Davis, Paul J., Wang, Kuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Association for Dental Sciences of the Republic of China 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6739295/
https://www.ncbi.nlm.nih.gov/pubmed/31528253
http://dx.doi.org/10.1016/j.jds.2019.01.013