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Intrinsic adriamycin resistance in p53-mutated breast cancer is related to the miR-30c/FANCF/REV1-mediated DNA damage response

Adriamycin(ADR) is still considered to be one of the most effective agents in the treatment of breast cancer (BrCa), its efficacy is compromised by intrinsic resistance or acquire characteristics of multidrug resistance. At present, there are few genetic alterations that can be exploited as biomarke...

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Detalles Bibliográficos
Autores principales: Lin, Shu, Yu, Lifeng, Song, Xinyue, Bi, Jia, Jiang, Longyang, Wang, Yan, He, Miao, Xiao, Qinghuan, Sun, Mingli, Olopade, Olufunmilayo I., Zhao, Lin, Wei, Minjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6739306/
https://www.ncbi.nlm.nih.gov/pubmed/31511498
http://dx.doi.org/10.1038/s41419-019-1871-z