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Intrinsic adriamycin resistance in p53-mutated breast cancer is related to the miR-30c/FANCF/REV1-mediated DNA damage response
Adriamycin(ADR) is still considered to be one of the most effective agents in the treatment of breast cancer (BrCa), its efficacy is compromised by intrinsic resistance or acquire characteristics of multidrug resistance. At present, there are few genetic alterations that can be exploited as biomarke...
Autores principales: | Lin, Shu, Yu, Lifeng, Song, Xinyue, Bi, Jia, Jiang, Longyang, Wang, Yan, He, Miao, Xiao, Qinghuan, Sun, Mingli, Olopade, Olufunmilayo I., Zhao, Lin, Wei, Minjie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6739306/ https://www.ncbi.nlm.nih.gov/pubmed/31511498 http://dx.doi.org/10.1038/s41419-019-1871-z |
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