Transforming growth factor (TGF)-β1-induced miR-133a inhibits myofibroblast differentiation and pulmonary fibrosis

Transforming growth factor (TGF)-β1, a main profibrogenic cytokine in the progression of idiopathic pulmonary fibrosis (IPF), induces differentiation of pulmonary fibroblasts to myofibroblasts that produce high levels of collagen, leading to concomitantly loss of lung elasticity and function. Recent...

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Detalles Bibliográficos
Autores principales: Wei, Peng, Xie, Yan, Abel, Peter W., Huang, Yapei, Ma, Qin, Li, Linghai, Hao, Junfeng, Wolff, Dennis W., Wei, Taotao, Tu, Yaping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6739313/
https://www.ncbi.nlm.nih.gov/pubmed/31511493
http://dx.doi.org/10.1038/s41419-019-1873-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6739313/
https://www.ncbi.nlm.nih.gov/pubmed/31511493
http://dx.doi.org/10.1038/s41419-019-1873-x

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