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Heterogeneity in The Mechanical Properties of Integrins Determines Mechanotransduction Dynamics in Bone Osteoblasts

Bone cells are exposed to dynamic mechanical stimulation that is transduced into cellular responses by mechanotransduction mechanisms. The extracellular matrix (ECM) provides a physical link between loading and bone cells, where mechanoreceptors, such as integrins, initiate mechanosensation. Though...

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Detalles Bibliográficos
Autores principales: Shuaib, Aban, Motan, Daniyal, Bhattacharya, Pinaki, McNabb, Alex, Skerry, Timothy M., Lacroix, Damien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6739315/
https://www.ncbi.nlm.nih.gov/pubmed/31511609
http://dx.doi.org/10.1038/s41598-019-47958-z