The molecular basis of chaperone-mediated interleukin 23 assembly control

The functionality of most secreted proteins depends on their assembly into a defined quaternary structure. Despite this, it remains unclear how cells discriminate unassembled proteins en route to the native state from misfolded ones that need to be degraded. Here we show how chaperones can regulate...

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Detalles Bibliográficos
Autores principales: Meier, Susanne, Bohnacker, Sina, Klose, Carolin J., Lopez, Abraham, Choe, Christian A., Schmid, Philipp W. N., Bloemeke, Nicolas, Rührnößl, Florian, Haslbeck, Martin, Bieren, Julia Esser-von, Sattler, Michael, Huang, Po-Ssu, Feige, Matthias J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6739322/
https://www.ncbi.nlm.nih.gov/pubmed/31511508
http://dx.doi.org/10.1038/s41467-019-12006-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6739322/
https://www.ncbi.nlm.nih.gov/pubmed/31511508
http://dx.doi.org/10.1038/s41467-019-12006-x

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