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The molecular basis of chaperone-mediated interleukin 23 assembly control
The functionality of most secreted proteins depends on their assembly into a defined quaternary structure. Despite this, it remains unclear how cells discriminate unassembled proteins en route to the native state from misfolded ones that need to be degraded. Here we show how chaperones can regulate...
Główni autorzy: | , , , , , , , , , , , , |
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Format: | Online Artykuł Texto |
Język: | English |
Wydane: |
Nature Publishing Group UK
2019
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Hasła przedmiotowe: | |
Dostęp online: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6739322/ https://www.ncbi.nlm.nih.gov/pubmed/31511508 http://dx.doi.org/10.1038/s41467-019-12006-x |