TGFβ blocks IFNα/β release and tumor rejection in spontaneous mammary tumors

Type I interferons (IFN) are being rediscovered as potent anti-tumoral agents. Activation of the STimulator of INterferon Genes (STING) by DMXAA (5,6-dimethylxanthenone-4-acetic acid) can induce strong production of IFNα/β and rejection of transplanted primary tumors. In the present study, we addres...

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Detalles Bibliográficos
Autores principales: Guerin, Marion V., Regnier, Fabienne, Feuillet, Vincent, Vimeux, Lene, Weiss, Julia M., Bismuth, Georges, Altan-Bonnet, Gregoire, Guilbert, Thomas, Thoreau, Maxime, Finisguerra, Veronica, Donnadieu, Emmanuel, Trautmann, Alain, Bercovici, Nadège
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6739328/
https://www.ncbi.nlm.nih.gov/pubmed/31511510
http://dx.doi.org/10.1038/s41467-019-11998-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6739328/
https://www.ncbi.nlm.nih.gov/pubmed/31511510
http://dx.doi.org/10.1038/s41467-019-11998-w

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