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Minimal intervening control of biomolecular networks leading to a desired cellular state
A cell phenotype can be represented by an attractor state of the underlying molecular regulatory network, to which other network states eventually converge. Here, the set of states converging to each attractor is called its basin of attraction. A central question is how to drive a particular cell st...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6739335/ https://www.ncbi.nlm.nih.gov/pubmed/31511585 http://dx.doi.org/10.1038/s41598-019-49571-6 |