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Minimal intervening control of biomolecular networks leading to a desired cellular state

A cell phenotype can be represented by an attractor state of the underlying molecular regulatory network, to which other network states eventually converge. Here, the set of states converging to each attractor is called its basin of attraction. A central question is how to drive a particular cell st...

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Detalles Bibliográficos
Autores principales: Choo, Sang-Mok, Park, Sang-Min, Cho, Kwang-Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6739335/
https://www.ncbi.nlm.nih.gov/pubmed/31511585
http://dx.doi.org/10.1038/s41598-019-49571-6