Molecular basis for metabolite channeling in a ring opening enzyme of the phenylacetate degradation pathway

Substrate channeling is a mechanism for the internal transfer of hydrophobic, unstable or toxic intermediates from the active site of one enzyme to another. Such transfer has previously been described to be mediated by a hydrophobic tunnel, the use of electrostatic highways or pivoting and by confor...

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Detalles Bibliográficos
Autores principales: Sathyanarayanan, Nitish, Cannone, Giuseppe, Gakhar, Lokesh, Katagihallimath, Nainesh, Sowdhamini, Ramanathan, Ramaswamy, Subramanian, Vinothkumar, Kutti R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6739347/
https://www.ncbi.nlm.nih.gov/pubmed/31511507
http://dx.doi.org/10.1038/s41467-019-11931-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6739347/
https://www.ncbi.nlm.nih.gov/pubmed/31511507
http://dx.doi.org/10.1038/s41467-019-11931-1

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