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Mitochondrial supercomplex assembly promotes breast and endometrial tumorigenesis by metabolic alterations and enhanced hypoxia tolerance

Recent advance in cancer research sheds light on the contribution of mitochondrial respiration in tumorigenesis, as they efficiently produce ATP and oncogenic metabolites that will facilitate cancer cell growth. Here we show that a stabilizing factor for mitochondrial supercomplex assembly, COX7RP/C...

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Detalles Bibliográficos
Autores principales: Ikeda, Kazuhiro, Horie-Inoue, Kuniko, Suzuki, Takashi, Hobo, Rutsuko, Nakasato, Norie, Takeda, Satoru, Inoue, Satoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6739376/
https://www.ncbi.nlm.nih.gov/pubmed/31511525
http://dx.doi.org/10.1038/s41467-019-12124-6