Cargando…
Mitochondrial supercomplex assembly promotes breast and endometrial tumorigenesis by metabolic alterations and enhanced hypoxia tolerance
Recent advance in cancer research sheds light on the contribution of mitochondrial respiration in tumorigenesis, as they efficiently produce ATP and oncogenic metabolites that will facilitate cancer cell growth. Here we show that a stabilizing factor for mitochondrial supercomplex assembly, COX7RP/C...
Autores principales: | Ikeda, Kazuhiro, Horie-Inoue, Kuniko, Suzuki, Takashi, Hobo, Rutsuko, Nakasato, Norie, Takeda, Satoru, Inoue, Satoshi |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6739376/ https://www.ncbi.nlm.nih.gov/pubmed/31511525 http://dx.doi.org/10.1038/s41467-019-12124-6 |
Ejemplares similares
-
Efp promotes in vitro and in vivo growth of endometrial cancer cells along with the activation of nuclear factor-κB signaling
por: Sato, Wataru, et al.
Publicado: (2018) -
Deficiency of COX7RP, a mitochondrial supercomplex assembly promoting factor, lowers blood glucose level in mice
por: Shiba, Sachiko, et al.
Publicado: (2017) -
Functional Mechanisms of Mitochondrial Respiratory Chain Supercomplex Assembly Factors and Their Involvement in Muscle Quality
por: Azuma, Kotaro, et al.
Publicado: (2020) -
MON-310 Oncogenic Roles of Tripartite Motif 25 in Endometrial Cancer
por: Horie-Inoue, Kuniko, et al.
Publicado: (2019) -
OR27-06 Identification And Functional Analyses Of Therapeutic Targets For Testicular Germ Cell Tumors
por: Horie, Kuniko, et al.
Publicado: (2023)