Interplay of miR-137 and EZH2 contributes to the genome-wide redistribution of H3K27me3 underlying the Pb-induced memory impairment

Compromised learning and memory is a common feature of multiple neurodegenerative disorders. A paradigm spatial memory impairment could be caused by developmental lead (Pb) exposure. Growing evidence implicates epigenetic modifications in the Pb-mediated memory deficits; however, how histone modific...

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Detalles Bibliográficos
Autores principales: Gu, Xiaozhen, Xu, Yi, Xue, Wei-Zhen, Wu, Yulan, Ye, Zi, Xiao, Guiran, Wang, Hui-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6739382/
https://www.ncbi.nlm.nih.gov/pubmed/31511494
http://dx.doi.org/10.1038/s41419-019-1912-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6739382/
https://www.ncbi.nlm.nih.gov/pubmed/31511494
http://dx.doi.org/10.1038/s41419-019-1912-7

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