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Interplay of Plasmodium falciparum and thrombin in brain endothelial barrier disruption

Recent concepts suggest that both Plasmodium falciparum factors and coagulation contribute to endothelial activation and dysfunction in pediatric cerebral malaria (CM) pathology. However, there is still limited understanding of how these complex inflammatory stimuli are integrated by brain endotheli...

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Detalles Bibliográficos
Autores principales: Avril, Marion, Benjamin, Max, Dols, Mary-Margaret, Smith, Joseph D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6739390/
https://www.ncbi.nlm.nih.gov/pubmed/31511575
http://dx.doi.org/10.1038/s41598-019-49530-1