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Putative link between Polo-like kinases (PLKs) and Toll-like receptor (TLR) signaling in transformed and primary human immune cells

Toll-like receptors (TLRs) are important sentinels of bacterial and viral infection and thus fulfil a critical sensory role in innate immunity. Polo-like kinases (PLKs), a five membered family of Ser/Thr protein kinases, have long been studied for their role in mitosis and thus represent attractive...

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Detalles Bibliográficos
Autores principales: El Maadidi, Souhayla, Weber, Alexander N. R., Motshwene, Precious, Schüssler, Jan Moritz, Backes, Daniel, Dickhöfer, Sabine, Wang, Hui, Liu, Xiao, Garcia, Magno Delmiro, Taumer, Christoph, Soufi, Boumediene, Wolz, Olaf-Oliver, Klimosch, Sascha N., Franz-Wachtel, Mirita, Macek, Boris, Gay, Nicholas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6739412/
https://www.ncbi.nlm.nih.gov/pubmed/31511529
http://dx.doi.org/10.1038/s41598-019-49017-z