Conserved Pseudoknots in lncRNA MEG3 Are Essential for Stimulation of the p53 Pathway

Long non-coding RNAs (lncRNAs) are key regulatory molecules, but unlike with other RNAs, the direct link between their tertiary structure motifs and their function has proven elusive. Here we report structural and functional studies of human maternally expressed gene 3 (MEG3), a tumor suppressor lnc...

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Detalles Bibliográficos
Autores principales: Uroda, Tina, Anastasakou, Eleni, Rossi, Annalisa, Teulon, Jean-Marie, Pellequer, Jean-Luc, Annibale, Paolo, Pessey, Ombeline, Inga, Alberto, Chillón, Isabel, Marcia, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6739425/
https://www.ncbi.nlm.nih.gov/pubmed/31444106
http://dx.doi.org/10.1016/j.molcel.2019.07.025

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6739425/
https://www.ncbi.nlm.nih.gov/pubmed/31444106
http://dx.doi.org/10.1016/j.molcel.2019.07.025

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